Ruthenium red-binding glycoprotein of the AH-130 ascites hepatoma cell surface and its biological activity
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چکیده
منابع مشابه
Metabolic-independent volume changes and Mg++ binding in mitochondria isolated from AH-130 Yoshida ascites hepatoma.
The mitochondria isolated in isotonic sucrose from AH-130 Yoshida ascites hepatoma appear spontaneously swollen (11, 12). This spontaneous swelling may be in part responsible for the inability of tumor mitochondria to undergo extensive volume changes in hypotonie conditions or in conditions that induce large-amplitude, metabolic-dependent, or metabolic-independent swelling in normal liver mitoc...
متن کاملRuthenium-red-induced cell agglutination and surface glycoprotein and mucopolysaccharide.
Ruthenium red induces the agglutination of ascites hepatoma cells. The agglutination was inhibited by acidic polysaccharides but not by haptenic inhibitors of some plant agglutinins. The agglutination was also abolished by treatment of the cells with a low concentration of papain. Papain digestion causes a decrease in the number of microvilli on the cell surface and the release of carbohydrate-...
متن کاملMarked hyperlipidaemia in rats bearing the Yoshida AH-130 ascites hepatoma.
Malignant tumour burden is a pathological s ta te associated with a considerable demand for nutrients by the growing tumour [l]. Although a great deal of work has been carried out, there are contradictory results about the effects of tumour burden on lipid metabolism both in experimental animals and man. Lipid oxidation has been reported either increased [2], unchanged [3] or decreased [4]. In ...
متن کاملLipid Peroxidation in Rat AH-130 Hepatoma Cells Enriched
Tumor cells generally display low lipid peroxidation. A low content of polyunsaturated fatty acids in membrane phospholipids is a possible cause of their decreased susceptibility to lipid peroxidation. To investigate the importance of substrate availability in eliciting lipid peroxidation and to study cell viability in conditions of stimulated lipid peroxidation, AH-130 hepatoma cells were enri...
متن کاملCarcinostatic effect of aliphatic aldehydes and aldehyde dehydrogenase activity in Ehrlich carcinoma, Sarcoma 180, and Yoshida AH 130 hepatoma.
The antitumor activity of 2,3-dihydroxybutyraldehyde on Ehrlich carcinoma, Sarcoma 180, and Yoshida AH 130 hepatoma, as well as the aldehyde dehydrogenase activity in these tumors, was studied. 2,3-Dihydroxybutyraldehyde at nontoxic doses (500 mg/kg body weight i.p. daily for 7 days) slowed down the growth of solid and ascites tumors in mice. The treatment completely prevented the development o...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1979
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.91.1-2_141